Lead in Drinking Water, Part 2 (Ethics)

research
lead
ethics
IRB
Author
Affiliation

Theodore A. Corcovilos

Published

April 19, 2018

Abstract
Before I describe how we measure lead in drinking water, I want to discuss some of the new (to me) meta issues associated with this project. A lot of these things are uncommon for physics research, but will be familiar to folks in biology or medicine. I am a rank amateur on these issues, so consider this an imperfect discussion by someone still finding his way.

Before I describe how we measure lead in drinking water, I want to discuss some of the new (to me) meta issues associated with this project. A lot of these things are uncommon for physics research, but will be familiar to folks in biology or medicine. I am a rank amateur on these issues, so consider this an imperfect discussion by someone still finding his way.

IRB

As a physicist, I was only vaguely aware of what an IRB was and the role it plays in research. IRB stands for Institutional Review Board. Under U.S. law, all research done on human subjects must be reviewed by an internal committee at the institution conducting the research to ensure that no harm or potential harm is done to subjects of the research. The IRB also reviews research on animal subjects to make sure the work is humane. Today it seems obvious that research should not needlessly endanger the subjects, but in the not-so-distant past an “ends justifies the means” attitude was taken by some scientists, particularly if the subjects were perceived as having less value than the average citizen. Racial and ethic minorities, prisoners, and the mentally impaired were all considered little better than animals by various researchers. And while it is easy to condemn the horrific work of Nazi scientists on Jews and other minorites during World War II, the United States has its own history of malicious research. A particularly vile example is the infamous Tuskegee Syphilis experiments in which unsuspecting African-American patients were deliberately infected with syphilis and intentionally denied treatment so that the scientists could study the progression of the disease. This lasted from the 1930s until it was shutdown by the government in 1972 thanks to a whistleblower leaking to the press and the subsequent public outrage.

Although IRBs were initially tasked with overseeing human research, they have expanded to cover animal subjects, and sometimes non-medical research on humans (e.g.~sociological surveys). The purpose of the latter type of review is not so much to prevent physical harm to subjects, but to prevent their information from being used against them. Typically, we require procedures to protect the identities of the subjects, for example.